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If you are consistently sleep-deprived, your body may struggle to maintain its antioxidant status, regardless of how many supplements you take

That doesnt mean that lower doses dont work

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The SURMOUNT-1 trial demonstrated average reductions of 15-22.5% of body weight over 72 weeks, depending on dose

Prevention of recurrent hepatitis C after liver transplantation with early interferon and ribavirin treatment.Transplant Proc 2001