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The second runs through RAS, RAF, MEK, and ERK1/2, which control cell-cycle entry and satellite-cell proliferation [5]

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Inhibition of key enzymes in the EMP pathway in CRC Elevated expression of critical EMP pathway enzymes drives therapeutic resistance in CRC, particularly to radiotherapy and chemotherapy [46]

Nevertheless, the direct effect of ZMTP nanosheet on the physiological activities of mBMSCs were first investigated by incubating mBMSCs directly with ZMTP or single MnTCPP + or Zn 2+ , and the CCK-8 results showed insignificant changes of the viability of mBMSCs even in 96 h of treatments in different groups (Fig