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For some patients, prednisone's appetite effect completely overrides semaglutide's suppressant action, making weight loss nearly impossible during high-dose corticosteroid therapy

Specific Risks of Semaglutide While generally considered safer due to its non-surgical nature, Semaglutide has specific medical considerations: Gastrointestinal Distress: About 60% of users experience mild-to-moderate GI issues, typically during the dose-escalation phase

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