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One example escalation schedule observed in Phase 2 obesity trials proceeded broadly as follows: Weeks 14: 2 mg once weekly (initiation phase) Weeks 58: 4 mg once weekly Weeks 912: 8 mg once weekly Weeks 13 onwards: Up to 12 mg once weekly (the maximum dose explored in Phase 2 trials) This is an illustrative example only

Personalized Approach Compounding pharmacies work with healthcare providers to create a prescription specifically designed for the patients unique health profile and goals

Potential win-win

Multiple autoimmune conditions responding simultaneously to a single intervention is unusual in rheumatology, where treatment typically requires different medications targeting different pathways

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Even without insurance, metformin is affordable compared to many diabetes drugs