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In contrast, ARG2 is expressed in mitochondria of multiple tissues, with the most abundant expression in the kidney and prostate, and mediates arginine/ornithine balance

Activated macrophages are generally categorized into two kinds: M1 macrophages, which participate in pro-inflammatory responses, and M2 macrophages, which engage in anti-inflammatory responses (84)

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We used the quantitative reverse transcription-polymerase chain reaction (qRT-PCR) to measure the relative mRNA expressions of activating transcription factor-4 (ATF4), CHOP-10, Glucose-Regulated Protein 78 (GRP78), and PERK as markers for ER stress

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