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Mast cells are now thought to also play a pathogenic role in the condition.[ref] Researchers have found that the average prostaglandin D2 levels (an indicator of mast cell activation) are higher in people with rheumatoid arthritis than in healthy controls.[ref] Related article : Rheumatoid arthritis genes Mast cells may play a role in obesity and diabetes: It has been known for a while that obesity is linked to increased systemic inflammation

However, the full benefits can take several weeks or months depending on the condition being addressed and the individuals response to treatment

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