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"While gastrointestinal side effects like nausea and constipation are common, they are usually temporary and manageable," she notes

The 14.9% mean weight loss at 68 weeks was unprecedented for a GLP-1 receptor agonist at the time

New oral GLP-1s are designed to protect peptides, the active ingredients in these medications, so they can survive the trip through your digestive tract

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Sign up for Guardian Australias breaking news email However, cost and supply issues have prompted health experts and advocates to call on governments to intervene and subsidise the drugs for obese people with health-related risk factors