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This is followed by the release of nesfatin-1 which stimulates cholecystokinin secretion leading to a rise in bile salts from gallbladder emptying, and the binding of Takeda P protein coupled receptor 5 (TGR5) onto the surface of the enteroendocrine cells, all of which eventually culminates in GLP-1 secretion [9]

10.1038/nm.3902 83 LovisaS.Fletcher-SananikoneE.SugimotoH.HenselJ.LahiriS.HertigA.et al (2020)

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Vitamin B12 enhances these effects by contributing to the production of red blood cells and improving oxygen delivery throughout the body, which supports endurance and energy expenditure

If you are unsure where to start or which dose is right for your specific goals, we recommend taking our Health Quiz

Sarcopenic obesity and metabolic syndrome in adult caucasian subjects