The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings
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Long-term storage at 20 C, protected from light
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The precise mechanisms by which GLP-1 receptor agonists may trigger headaches are not fully elucidated , but several plausible physiological explanations exist