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These include: Nausea (the most common complaint, particularly in the first few weeks) Vomiting Diarrhoea or constipation Decreased appetite (which, while therapeutically desirable, can occasionally be excessive) Abdominal discomfort or bloating Injection-site reactions (such as redness, itching, or mild swelling at the injection site) Headache, dizziness, and fatigue , particularly during early treatment These effects are generally dose-dependent and tend to diminish as the body adjusts to the medication
J Am Med Assoc
Designing hydrogels for controlled drug delivery
Nature 566 , 4950 (2019)
GLP-1 Receptor Agonist Discontinuation Among Patients With Obesity and/or Type 2 Diabetes
13, 2022, article 951186
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