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129 In addition, the cholesterol homeostasis of cells is essential for the insulin secretion, as accumulated cholesterol in the plasma membrane resulting in impaired secretion via exocytosis, and reduced cholesterol in insulin granules making them enlarged, also resulting in secretory dysfunction
Glucose-6-phosphate dehydrogenase (G6PD) deficiency increases the vulnerability of erythrocytes to oxidative stress
It is because of its ability to transport fatty acids into your cells mitochondria
(2019) 144:10917.e4
[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care