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Cold Spring Harb Perspect Biol (2012) 4:a006049.10.1101/cshperspect.a006049 29 BarjestehNBehboudiSBrisbinJTVillanuevaAINagyESharifS

The compounds dual-agonism profile has attracted broad research attention, spanning metabolic biology, endocrinology, and receptor pharmacology

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However, DMF can also mediate pro-ferroptosis effects by GSH succinylation 55 , impairs NF-B/STAT3 signaling 56 , and potentiates oxidative cell death 57

It has been observed to increase lipolysis, which is the breakdown of fat, and reduce lipogenesis, the process of transforming non-fat food materials into body fat

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