These affects were BA-dependent because (1) depletion of the BA receptor FXR and (2) genetic deletion of a BA-metabolizing enzyme abrogated these affects (174)
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Among other studies, TurboID has played a crucial role in exploring the nuclear pore complex (NPC) and mitochondrial proteins as potential drug targets in Plasmodium , the parasite responsible for malaria
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Gastrointestinal Health Problems Linked to Saxenda Use In addition to a heightened risk of pancreatitis and gallstones highlighted above, Saxenda patients have also suffered from the following serious gastrointestinal issues: Severe and Prolonged Vomiting While nausea and some vomiting are normal side effects when taking Saxenda, some patients vomit several times a day for two weeks or more
They highlight that the study only shows that users reported these symptoms while taking the medications, not that the GLP-1 drugs directly caused them