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Further research of in vivo and in vitro treated hepatocytes and liver fractions would complement our findings

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In ovarian or breast cancers, cyclodextrins may be used in combination with nanoparticles to provide controlled and targeted delivery of drugs, namely tamoxifen [204] or etoposide, to the tumor, thereby reducing the required systemic dose [205]

Furthermore, metformin treatment alleviated H 2 O 2 -induced oxidative damage and enhanced the nuclear translocation of Nrf2 in the chondrocytes exposed to H 2 O 2 (Figs