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injections of either saline or Ex-4c (1 g) to Pomc -hrGFP mice and sacrificed them after 2 hours to assess Fos expression, a marker of increased neuronal activity

This can result in scarring, extended recovery times, and the need for further medical treatment

3 Importantly, there is no increase in melanocyte number

Microdosing GLP-1 refers to starting with lower-than-standard doses of glucagon-like peptide-1 receptor agonists, including drugs like Ozempic and Mounjaro

There is limited direct evidence for this specific stack in controlled studies, and clinicians considering it should weigh the additive mechanistic logic against the absence of human safety data for the combination