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Table 3 Results of a 52-week Monotherapy Trial in Adults with Type 2 Diabetes Mellitus a Figure 3 Mean HbA 1c for Adult Patients with Type 2 Diabetes Mellitus who Completed the 52-week Trial and for the Last Observation Carried Forward (LOCF, intent-to-treat) data at Week 52 (Monotherapy) Combination Therapy Add-on to Metformin In this 26-week trial, 1,091 adult patients with type 2 diabetes mellitus were randomized to liraglutide injection 0.6 mg, liraglutide injection 1.2 mg, liraglutide injection 1.8 mg, placebo, or glimepiride 4 mg (one-half of the maximal approved dose in the United States), all as add-on to metformin

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And states are "between a rock and a hard place," said Kody Kinsley, who until January led North Carolina's Health and Human Services Department

Newer Doesnt Mean Safer Mounjaro and Zepbound are newer and may produce faster weight loss, but: They use the same gastric-slowing mechanism Long-term safety data is still limited Early reports suggest similar serious complications Being newer means manufacturers had access to earlier safety signals from semaglutide 4

This and other trials have shown improvements in patients lipid profiles with the most pronounced impact on reduction of triglycerides

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