CMS-0057-F and What It Changes for PA in 2026 The CMS Interoperability and Prior Authorization Final Rule (CMS-0057-F) is the most significant federal PA reform in a decade
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One significant finding is from the SELECT trial, which showed that long-term use of semaglutide in individuals with obesity but without diabetes led to a 20% reduction in major cardiovascular events and an average weight loss of 9.4%
