The GLP-1 receptor activation slows gastric emptying, reduces appetite through hypothalamic signaling, and enhances insulin secretion in a glucose-dependent manner
Thus, platelets play a central role during tissue attrition (wounding) because they assist in hemostasis, innate immunity, anti-infection activity, inflammation and the secretion of a myriad of factors (including growth factors for stimulating the production of blood cells in bone marrow, chemokines to attract innate immune cells, reparative cytokines, and other biological response modifiers (BRMs) with a variety of functions) [9,10,11]

The search strategy involved using the following keywords either individually or in combination: (Coenzyme Q10 OR Dehydroepiandrosterone OR Melatonin OR Resveratrol OR 2 - Oxoglutaric acid OR Allantoin OR Apigenin OR Berberine OR Capsaicin OR Chrysin OR Curculigoside OR Curcumin OR Daphnetin OR Diosgenin OR Epigallocatechin Gallate OR Eugenol OR Gallotannin OR Honokiol OR Icariin OR leonurine hydrochloride OR Nicotinamide mononucleotide OR Nobiletin OR Paeoniflorin OR Procyanidin OR Pterostilbene OR Puerarin OR Rutin OR Scutellarin OR Spermidine OR Sphingosine 1-phosphate OR -Ketoglutarate) AND (Diminished ovarian reserve OR Poor ovarian response) AND (IVF OR ICSI OR ART OR Assisted reproductive technology) AND (Randomized controlled trial OR RCT)
Administration route is determined by the prescribing physician based on the patient's indication and clinical assessment
Effective formulations typically contain 0.5-2% GHK-Cu
Dosage should be determined through individual clinical assessment with a qualified healthcare provider