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HM-15275 is the only small-molecule modulator in the clinical stages of the field - every other Phase 1/2/3 asset is a peptide, an Fc fusion, or an antibody-drug conjugate

Indian J Med Res 150(4):412416

Testing has revealed contamination rates between 12-58%, with 30% of products containing incorrect amino acid sequences and 65% exceeding endotoxin safety thresholds

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Convenience is not a substitute for evaluation

Lipoprotein (a) levels are associated with aortic valve calcification in asymptomatic patients with familial hypercholesterolaemia