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Moreover, paclitaxel has also been reported to induce neurotoxicity, primarily by affecting neural stem cells and progenitor cells in the hippocampus, which leads to impaired spatial memory ( 6 Activation of neuronal apoptosis Apoptosis, also known as programmed cell death, is a tightly regulated physiological process that is essential for maintaining cellular homeostasis by eliminating damaged, dysfunctional, or excess cells without triggering inflammation (Yuan and Ofengeim, 2023)

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