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In 1999, Gutzwiller et al

Food intake, body weight, and energy expenditure in diet-induced obesity mice and rats Male diet-induced obese (DIO) C57Bl/6J mice, sourced from Charles River, France, aged 25 weeks (weighing 3956 g), were maintained on a 60% high-fat diet (HFD, D12492, Research Diets, Inc.) for 24 weeks

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That investigation has now occurred (at least in preliminary form), and the human results are more reassuring than the animal data suggested

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The column was pre-equilibrated with 20 mM HEPES, pH 7.4, 100 mM NaCl, 5 M GLP-2, 100 M TCEP, 2 mM MgCl 2 , 0.00075% (w/v) LMNG, 0.00025% (w/v) GDN and 0.0002% (w/v) CHS