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3-adrenergic agonists enhance thermogenesis by activating Uncoupling Protein 1 (UCP1) in brown adipose tissue, which stimulates PKA-mediated lipolysis and increases energy expenditure [42]

Arana A, Morton NS, Hansen TG

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In addition, patients on tirzepatide in the SUMMIT trial experienced improved symptoms and a reduced risk of cardiovascular death or worsening heart failure

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Do Not Take If : You have pre-existing liver or kidney conditions, or are pregnant or breastfeeding, without consulting a healthcare provider