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Additionally, the anti-inflammatory properties of this ingredient reduce scalp inflammation that can damage follicles and impede growth, while its antioxidant capabilities protect against free radical damage that accelerates follicular aging

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doi: 10.3390/nu12020334 134 Garca-GarcaFJMonistrol-MulaACardellachFGarrabouG

278 Additionally, MSCs-EVs modulate macrophage phenotypes and enhance polarization to the anti-inflammatory and highly phagocytic phenotype, which mainly depends on improved macrophage oxidative phosphorylation in mitochondria due to EV-mediated mitochondrial transfer

However, these spikes operate on shorter timescales than the calcium transients and the longer temporal decay of intracellular calcium (on the order of tens of seconds, Fig 3) may be crucial for the negative feedback of the GPCR pathway