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Fei LW, Wang Y, Chen SX (2009) Improved glutathione production by gene expression in Pichia pastoris

The standard dose escalation schedule reflects this predictability: At each dose, four weeks allows the drug to reach steady state at that level before judging efficacy

Regular monitoring of kidney function is important for those at risk

These results demonstrate, for the first time in depressed adolescents, that fluoxetine has immediate neural effects on core components of the cortico-limbic circuitry prior to clinical changes in mood