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For rate analysis of G protein BRET assays, data were fitted to a one-phase association curve in Graphpad Prism

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The underlying mechanisms of paclitaxel-induced white matter damage have not yet been reported but may involve mitochondrial dysfunction, oxidative stress, and neuroinflammation (Xu et al., 2022)

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Figure 3 With these features in mind, the difference between classes has been simply analyzed by looking at some specific criteria: (i) the percentage identity, (ii) the size of the proteins, (iii) the presence of extra domains, and (iv) the presence of three specific signatures, i.e