Men 9% currently using Growth Rate: 587% increase in prescriptions from 2019 to 2024 The Numbers Tell the Story: According to a November 2025 KFF Health Tracking Poll, one in eight American adults is currently taking a GLP-1 drug like Ozempic or Wegovynearly double the rate from just 18 months ago
These medications, including semaglutide and tirzepatide, work by mimicking hormones naturally produced in your intestines that regulate blood sugar and appetite
Additionally, metformin may influence lipid metabolism, smooth muscle contractions of the vascular system, hypercoagulation, platelet hyperactivity, calcium handling within cardiomyocytes and endothelial cell function [34]
This inflammatory environment impacts barrier integrity and provides an avenue for the entry of luminal contents into systemic circulation contributing to the development of gut-associated and extraintestinal inflammatory disorders
Patients cannot self-prescribe or initiate a compounding request without a providers involvement
but the test is not specific, as a positive result may or may not be indicative of lupus