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This peak usually occurs around 1 to 3 days after your dose

While diet can support your bodys natural GLP-1 response, it cant replicate the effects of these medications

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Oral semaglutide has been on the market to treat type 2 diabetes since 2019

Interestingly, GLP-1 is also known to decrease the rewarding effects of food intake by interacting with parts of the mesolimbic dopamine system such as the ventral tegmental area (VTA), nucleus accumbens (NAc) [34], and also GABAergic circuits in the laterodorsal tegmental nucleus (LDTg) [35], which makes brain GLP-1R signaling a promising target for the treatment of alcohol and cocaine abuse disorders [36, 37]

[1] [2] Semaglutide has an additional warning regarding worsening of diabetic retinopathy complications, particularly in patients with pre-existing retinopathy who experience rapid improvement in blood glucose