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Problems with orexin production can cause various rest disorders

Semaglutide does not directly affect exercise performance, but the reduced caloric intake can lead to decreased energy during workouts, especially in the first months

| 07.22.25 | 3 min read

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The peptide works specifically on adipose tissue through beta-3 adrenergic receptor modulation, triggering lipolysis while inhibiting lipogenesis, without affecting growth hormone levels, insulin sensitivity, or other metabolic systems

For more detail on the diluent side of this equation, see our guide on how long bacteriostatic water lasts