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This is the trial that will settle the debate

Q3: For a long term wellness strategy what are the dependency risks of an NAD supplement?: NAD supplements do not create chemical dependency like stimulants

First, the chemical identification was performed once, with the methodology of the 1970s, and was not subsequently re-verified by modern peptide sequencing a point Kovalzon and Strekalova later flagged as a source of doubt about whether the isolated nonapeptide was a single defined entity or a mischaracterized fraction of a larger precursor (Kovalzon & Strekalova, 2006)

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10.1371/journal.pone.0066418 58