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In the UK, adults with confirmed B12 deficiency and neurological symptoms typically receive hydroxocobalamin injections1 mg intramuscularly on alternate days until symptoms stabilise, followed by maintenance doses every two months

In other embodiments, PLGA copolymers with polyethylene glycol (PEG) are suitable polymeric matrices for the formulations disclosed herein

In some embodiments, the auris-acceptable formulations or compositions described herein are gel formulations or gel compositions

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Comment: A commenter recommended evaluating receiving facilities instead of REHs for numerator component (3) which evaluates the time from Decision to Transfer (order) to the ED departure

Levocarnitine is an amino-acid derivative essential for mitochondrial fatty-acid transport, and this injectable formulation is used to treat or prevent clinically significant carnitine deficiency in conditions such as primary systemic carnitine deficiency, certain inborn errors of metabolism, and end-stage renal disease on dialysis