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Biochim Biophys Acta 1837(1):5162 Zhou R, Pantel AR, Li S et al (2017) [(18)F](2S,4R)4-Fluoroglutamine PET detects glutamine pool size changes in triple-negative breast cancer in response to glutaminase inhibition

332,333 The expression of HIF-2 is unaffected by prolonged hypoxia, thus, there is a shift in the quanlitative nature of HIF away from subunit 1 and towards subunit 2

Monitor appetite, side effects, and weight over the first four weeks

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If youre unsure, contact your prescriber for guidance