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In our analysis, we further strengthened this perspective by demonstrating that, although the overall trend supports an association between the IGF axis and colorectal carcinogenesis, including precancerous lesions, the pooled effects of the WMDs should be interpreted with great caution due to the considerable heterogeneity observed across studies [4]
Maussang D, Rip J, van Kregten J, van den Heuvel A, van der Pol S, van der Boom B, et al
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