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The drug was a central part of the plot of the hugely popular novel Valley of the Dolls (1966) by Jacqueline Susann in which three highly successful Hollywood women each fall victim, in various ways, to the drug

Furthermore, these macrophages are morphologically distinct from collagen degrading macrophages

Accelerates metabolism and has an antiviral effect

No serious adverse events were reported, indicating a favorable safety profile for this combination approach (272)

It reduces oxidative stress and inflammation, major contributors to heart disease

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