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They do not, except at one downstream point of overlap

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Plasma was isolated by centrifugation at 17,000 g for 5 min at 4 C and diluted 1:10 in 50% (v/v) glycerol in PBS (pH 7.4) (Sigma-Aldrich) for storage at 20 C until analysis

Although FOXO4 is present in a small fraction of normal cells, its expression is significantly increased in senescent cells 34