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Fmoc-Thr(α-Gal β(1-3)GalNAc)-OH
mimicking the inner N-glycan substructure released by endo-β-mannosidase activity
This compound presents a tri-antennary 6'-sialyl-LacNAc (6SLN3) N-glycan on an Asn core with a PEG8-biotin tag
enabling enzymatic extension to sialylated and fucosylated structures such as sialyl-LacNAc and Lewis antigens
The biotin tag enables immobilization on streptavidin/neutravidin-coated platforms for binding studies and glycan arrays
AG623005: α-D-Man-Ethyl-Amine Pack Size:25 mg Fmoc-Thr(α-Gal β(1-3)GalNAc)-OHC8H17NO6 223. 22 An D mannose ligand equipped with an amine functionalized linker through a short ethyl spacer. The primary amine can be covalently coupled with N hydroxysuccinimide (NHS) activated esters to form stable amide bonds, providing a straightforward route to conjugate the ligand onto NHS activated molecules and surfaces. This compound provides an D mannose building block for glycoconjugate synthesis and the construction of probes for
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