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doi: 10.1016/j.cmet.2015.05.016

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Mast cell (MC)-derived histamine and H4R drove experimental colitis, as H4R / mice had lower symptom scores, neutrophil-recruitment mediators (colonic interleukin-6 (IL-6), CXCL1, CXCL2), and mucosal neutrophil infiltration than wild-type (WT) mice, as did MC-deficient Kit W-sh/W-sh mice reconstituted with histidine decarboxylasedeficient ( HDC / ) bone marrowderived MCs compared with WT-reconstituted mice

Randomly selecting individuals from a group in a culture or in the field is good practice for statistical reasons, but unless individuals are truly isolated from each other in their culture tanks so that no sensory contact is possible, pre-experimental contact/experiences cannot be ruled out

Wu T, Little TJ, Bound MJ et al (2016) A protein preload enhances the glucose-lowering efficacy of vildagliptin in type 2 diabetes

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