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The drug also helps people get better insulin sensitivity, and that is good for those who have diabetes or health conditions linked to their metabolism

While GLP-1 RAs are not typically prescribed solely as injectable treatments for depression, their impact on overall well-being, including mood, is a significant area of ongoing research

With regards to symptom improvement, while there was a substantial reduction in IBS-SSS (as well as GSRS sub scores for diarrhea, bloating and pain), change in IBS-SSS was not correlated with changes in GLP-1

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doi: 10.1016/S2213-8587(21)00113-3

Semaglutide versus placebo in patients with heart failure and mildly reduced or preserved ejection fraction: a pooled analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM randomised trials