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592,593 Moreover, due to the decrease of 3-hydroxykynurenine (a cytotoxic metabolite of KMO), the mice that lack active kynurenine 3-monooxygenase (KMO) will not develop into AKI after I/R injury

[DOI] [PubMed] [Google Scholar] 80.Robledinos-Anton N., Fernandez-Gines R., Manda G., Cuadrado A

Mutational analysis targeting either repeat 1 or repeat 2 of the N domain did not significantly impair complex assembly (Supplementary discussion and Supplementary Fig

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These early benefits reflect the anti-inflammatory properties of both peptides rather than structural tissue repair, which requires longer timeframes