GLP-1 receptor agonists, like semaglutide and tirzepatide, have helped many people manage weight and metabolic health more effectively, but if you're feeling tired, sluggish, or mentally foggy after starting treatment, you may not be alone
Insurance coverage for Mounjaro often comes with prior authorization requirements, step therapy mandates, and coverage denials for weight loss useeven though tirzepatide is FDA-approved for this indication
If tolerated well and improvements continue, they may maintain or cautiously increase to 300400 mcg every other day or daily depending on individual response
Nature 180:3738
While you should always take unvetted social media advice with a grain of salt, this one may have some truth to it
STEP UP trial: Semaglutide 7.2 mg in adults with obesity without type 2 diabetes [Conference presentation]