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However, B12 injections do not directly cause weight loss or significantly increase metabolism in people who already have adequate B12 levels

This is a novel integrated neurohormonal strategy recently employed for obesity drug development

You can give the shot at a 90-degree angle if 2 inches of skin can be grasped between your thumb and first (index) finger

It is also banned by the World Anti-Doping Agency, meaning competitive athletes cannot use it without risking a positive drug test and sanctions

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So far, most of the evidence comes from lab and tissue-sample studies rather than large human trials