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The expression of NtMEK2 DD induced the generation of hydrogen peroxide and up-regulated the expression of defense-related genes including PR- genes, peroxidases and GSTs including GSTTU4 and GSTTU12 (Jeong et al., 2008)

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To minimize potential side effects such as bruising and discoloration, clients will be advised to avoid anti-inflammatory medications and alcohol in the week leading up to the treatment