Balram Bhargava, Secretary Department of Health Research, Ministry of Health and Family Welfare, and Director General, Indian Council of Medical Research (ICMR), New Delhi for providing computational facilities
Sumithran P, Prendergast LA, Delbridge E, et al
Other methods under investigation include ultrasound-driven microbubble cavitation and magnetothermal nanocomposites activated by alternating magnetic fields (AMF), which can mechanically or thermally disrupt endosomal membranes deep within tissues, enabling spatiotemporal precision in cargo release [540543]
For the hepsin / mice, the timing of mortality was such that it occurred prior the onset of liver repair and regeneration processes, thereby confirming the role of hepsin in determining the mechanism of APAP toxicity tolerance during the early phase of drug exposure
FUNDING None
Adv Drug Deliv Rev 60(15):16631673 Mazet R et al (2020) Recent advances in the design of topical ophthalmic delivery systems in the treatment of ocular surface inflammation and their biopharmaceutical evaluation