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If you dont have a vitamin B12 deficiency to begin with or you dont first address the underlying causes of a deficiency, high doses of vitamin B12 will not work to improve your quality of life

1996, pp

[DOI] [PMC free article] [PubMed] [Google Scholar] 67.Jeong C, Han N, Jeon N, Rhee S, jin, Staatz CE, Kim MS, et al

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In the absence of amino acids such as cystine, cells promote translation of ATF4 via the general control non-repressor 2 (GCN2) -eukaryotic initiation factor (eIF2a) signaling pathway, which promotes transcription of genes involved in amino acid metabolism and stress response, including SLC7A11, enabling cells to cope with amino acid starvation