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I., Bruinstroop, E., Heijboer, A

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According to the FDA, the data showed no increased risk of suicide, depression, anxiety, or related psychiatric effects compared to placebo, leading the agency to conclude that the existing warnings are not supported by the evidence

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Less frequent AEs like hypoglycemia, is mostly seen in combination with insulin or sulfonylureas (157) and some reports of pancreatobiliary complications are partially explained by direct altered absorption of bile acids, rapid weight loss or changes in the gallbladder motility with increased risk of pancreatitis, even though it is extremely rare (160)