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TRIUMPH-4: Osteoarthritis pain signal Because TRIUMPH-4 specifically enrolled participants with symptomatic knee osteoarthritis, it also collected WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) pain data

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These systems include central neural circuits involved in appetite regulation, satiety signals, and energy homeostasis, as well as peripheral metabolic processes that regulate adipose tissue function, insulin sensitivity, and gonadal axis activity

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