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However, no significant interaction was found between APO4 status and tocopherol levels in predicting amyloid or tau pathology, indicating that while vitamin E may support cognitive resilience, its effects may not be strong enough to counteract APO4-related neuropathological changes [9,12]

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Structurally optimized derivatives like CMC2.24 demonstrate enhanced efficacy, inhibiting tyrosinase activity in MNT-1 human melanoma cells at 525 M without cytotoxicity (Goenka et al., 2021)

Prolonged exposure to light, elevated temperature, or aqueous environments may reduce stability