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Topisirovic, I., Svitkin, Y
Recent investigations (Kwon et al.) have identified AOD 9604 as a chondroprotective agent
Its levels vary throughout the body, reaching up to 10 mM in liver cells while other cells maintain millimolar concentrations
It is primarily investigated for its role in satiety signaling, food intake regulation, and metabolic homeostasis pathways
Early data has looked at medications such as methotrexate, mycophenolate mofetil (Cellcept) and azathioprine (Imura) given during the course of pegloticase treatment, and the results to date have been very encouraging
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