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Since the oral form of the peptide is not available commercially and injection of the peptide is not approved by the FDA, no metabolism experiments could be performed in humans If we go back to the 2014 review of six randomized, double-blind, placebo-controlled trials involving just over 900 patients, we see the following results: AOD9604 had no effect on serum IGF-1 levels, which confirms the hypothesis that AOD9604 does not act via IGF-1