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Postmortem examination of patients with purpura fulminans and IMD revealed meningococcal microcolonies associated with the endothelium of different vessels of the two barriers, such as the capillaries of the choroid plexuses, meningeal vessels, and brain parenchyma vessels (Mairey et al., 2006

a , Hydroxylation of C 2 would preclude the incorporation of an O 18 label as no equilibrium between a ketone and a gem-diol form exists for this hydroxylation product

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