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Elderly patients do not require dose adjustments based solely on age, though careful monitoring for tolerability is appropriate given potential age-related comorbidities

Clinical evidence from the STEP trials demonstrated that higher doses produce greater weight loss, with the 2.4 mg dose resulting in approximately 15% body weight reduction over 68 weeks compared to placebo

10.1016/j.regpep.2008.07.003 [DOI] [PubMed] 35.Jones KL, Rigda RS, Buttfield MDM, et al

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This intranasal delivery method can enhance the overall efficiency and bioavailability of peptide therapy while potentially reducing the risk of systemic side effects